CancerTracer: a curated database for Intrapatient Tumor Heterogeneity
●Results:
| Cancer Type | Patient Details | Trunk Mutation | Branch Mutation | Private Mutation |
|---|
| Endometrial Cancer | p030_MSKA1 | ARID1A,ARID1A,ARID5B,CCND1,CDKN1B,CUL3,DACH1,KMT2D,NIPBL,PIK3CA,PTEN,SMARCA4 |
- |
RB1 |
| Endometrial Cancer | p042_EC007 | PTEN(p.R130G) |
TP53(p.R273C),TP53(p.P72fs),NF1(p.L626fs),NF1(p.T767fs),SMARCA4(p.295fs),NOTCH1(p.V276M),NOTCH1(p.V964M),TET2(p.S838fs),TP53(p.G361fs),SMARCB1(p.R37S),TSC1(p.W750L),RET(p.P841L) |
CDK4(p.G29D),ERBB4(p.P940S),APC(p.G253S),NOTCH1(p.P2340fs) |
| Endometrial Cancer | p042_EC008 | PTEN(splice site),APC(frame shift deletion) |
1q amp,20p del |
- |
| Endometrial Cancer | p042_EC012 | PTEN(nonsense),FGFR2(missense) |
CTNNB1(missense) |
PIK3CA(frameshift),ARID1A(nonsense),CTCF(frameshift),ESR1(missense),ERBB3(frameshift) |
| Endometrial Cancer | p042_EC025 | PTEN(Missense),FGFR2(Missense),NF1(Missense) |
PIK3CA(missense),FLT3(missense) |
- |
| Endometrial Cancer | p042_EC028 | PIK3CA(missense),TP53(missense) |
- |
- |
| Endometrial Cancer | p042_EC030 | FGFR2(missense),KRAS(missense),MYCN(missense) |
- |
- |
